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KMID : 0043320110340071045
Archives of Pharmacal Research
2011 Volume.34 No. 7 p.1045 ~ p.1053
Antiretroviral therapy 2010 update: Current practices and controversies
Grant Matthew

Samuel Rafik
Bettiker Robert L.
Suh Byung-se
Abstract
Over the past four years, significant advances have been made in human immunodeficiency virus (HIV) therapy. In addition to the release of two new classes of antiretrovirals, our understanding of the older antiretrovirals continues to improve. Multiple combination pills have been brought to market, simplifying the regimens for patient ease. New controversies have arisen, notably the role of antiretrovirals in the chronic inflammatory state that HIV infection produces, which may lead to excess cardiac, renal, and hepatic mortality. The optimum time to initiate antiretroviral therapy remains unknown but clinicians are treating HIV infection earlier in its course. In this article, we review these and other new issues relating to the care of the HIV patient.
KEYWORD
HIV, Acquired immune deficiency syndrome (AIDS), Antiretroviral therapy
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